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Medical management of aortic disease in Marfan syndrome

	author = {Syed Usman Bin Mahmood and Camilo A. Velasquez and Mohammad A. Zafar and Ayman A. Saeyeldin and Adam J. Brownstein and Bulat A. Ziganshin and John A. Elefteriades and Sandip K. Mukherjee},
	title = {Medical management of aortic disease in Marfan syndrome},
	journal = {Annals of Cardiothoracic Surgery},
	volume = {6},
	number = {6},
	year = {2017},
	keywords = {},
	abstract = {Marfan syndrome (MFS) is a hereditary disorder with numerous pathophysiological effects, some specifically creating elastic dysfunction in cardiovascular organs. Aortic dilatation, dissection and rupture are major concerns in the management of MFS patients. Predilection to form aneurysms is an indication for prophylactic medical management of thoracic aortic aneurysm disease in these patients. The current guidelines describe β-blockers as the standard of care with angiotensin receptor blockers (ARBs) emerging as an equal, if not better alternative. We elaborate current evidence for and against different medical regimens used for the medical management of MFS patients.},
	issn = {2225-319X},	url = {}