@article{ACS16683,
author = {Karthik Thangappan and Awais Ashfaq and Chet Villa and David L. S. Morales},
title = {The total artificial heart in patients with congenital heart disease},
journal = {Annals of Cardiothoracic Surgery},
volume = {9},
number = {2},
year = {2020},
keywords = {},
abstract = {Background: While ventricular assist devices (VADs) remain the cornerstone of mechanical circulatory support (MCS), the total artificial heart (TAH-t) has gained popularity for certain patients in whom VAD support is not ideal. Congenital heart disease (CHD) patients often have barriers to VAD placement due to anatomic and physiological variation and thus can benefit from the TAH-t. The purpose of this study is to analyze the differences in TAH application and outcomes in patients with and without CHD.
Methods: The SynCardia Department of Clinical Research provided data upon request for all TAH-t implantations worldwide from December 1985 to October 2019. These patients were divided into two groups by pre-implantation diagnosis of CHD and non-CHD.
Results: A total of 1,876 patients were identified. Eighty (4%) of these patients also carried a diagnosis of CHD. There was a higher proportion of children in the CHD cohort (16.3% vs. 2.1%, P},
issn = {2304-1021}, url = {https://www.annalscts.com/article/view/16683}
}