@article{ACS16567,
author = {Massimo Boffini and Erika Simonato and Davide Ricci and Fabrizio Scalini and Matteo Marro and Stefano Pidello and Matteo Attisani and Paolo Solidoro and Paolo Olivo Lausi and Vito Fanelli and Cristina Barbero and Luca Brazzi and Mauro Rinaldi},
title = {Extracorporeal membrane oxygenation after lung transplantation: risk factors and outcomes analysis},
journal = {Annals of Cardiothoracic Surgery},
volume = {8},
number = {1},
year = {2019},
keywords = {},
abstract = {Background: Lung transplantation is the treatment of choice for end-stage pulmonary disease in selected patients. However, severe primary graft dysfunction is a significant complication of transplant and requires the implantation of an extracorporeal support. The aim of the study is to evaluate the impact of extracorporeal membrane oxygenation (ECMO) after transplant in our center.
Methods: From January 2008 till June 2018, 195 consecutive unselected patients receiving a lung transplant were considered. Mean age was 49±15 years. Main indications for transplant were idiopathic pulmonary fibrosis in 72 patients, chronic obstructive pulmonary disease in 60 patients, and cystic fibrosis in 40 patients. Prior to transplant, 18 patients were on mechanical ventilation and 14 were on ECMO.
Results: Twenty-five patients required venous-venous ECMO after transplant. Vascular disease as cause of transplant [relative risk (RR) 7.8, 95% CI: 1.5–41, P=0.02], donor age (RR 1.6, 95% CI: 1.03–2.3, P=0.03) and need for cardiopulmonary by-pass during transplant (RR 3.1, 95% CI: 1.02–9, P=0.04) were associated with ECMO implantation. Patients requiring post-transplant ECMO received more transfusions (P},
issn = {2304-1021}, url = {https://www.annalscts.com/article/view/16567}
}