%0 Journal Article
%T Results of frozen elephant trunk from the international E-vita Open registry
%A Tsagakis, Konstantinos
%A Pacini, Davide
%A Grabenwöger, Martin
%A Borger, Michael A.
%A Goebel, Nora
%A Hemmer, Wolfgang
%A Santos, Alvaro Laranjeira
%A Sioris, Thanos
%A Widenka, Kazimierz
%A Risteski, Petar
%A Mascaro, Jorge
%A Rudez, Igor
%A Zierer, Andreas
%A Mestres, Carlos A.
%A Ruhparwar, Arjang
%A Bartolomeo, Roberto Di
%A Jakob, Heinz
%J Annals of Cardiothoracic Surgery
%D 2020
%B 2020
%9 
%! Results of frozen elephant trunk from the international E-vita Open registry
%K 
%X Background: Over the years, frozen elephant trunk (FET) has become the treatment of choice for multisegmental thoracic aortic disease. This multicenter study presents the evolution of FET results using the E-vita Open hybrid graft with respect to institutional experience and time.  Methods: The data of International E-vita Open registry were studied according to the institutional experience of the participating centers (high- versus low-volume centers) and according to the evolution of FET treatment during time (1st period, 2005–2011 versus 2ndd period, 2012–2018). Overall, 1,165 patients were enrolled in the study with a wide variety of multisegmental thoracic aortic pathologies and aortic emergencies. Participating centers determined their own surgical protocol.  Results: The overall 30-day mortality was 12%. Short- and long-term survival were higher in high- versus low-volume centers (P=0.048 and P=0.013, respectively). In the 2nd time period, cerebral complications were reduced significantly (P=0.015). Incidence of permanent spinal cord-related symptoms was reduced to 3% in the 2nd time period, but did not reach statistical significance. Hypothermic circulatory arrest time (P
%U https://www.annalscts.com/article/view/16715
%V 9
%N 3
%P 178-188
%@ 2304-1021