TY - JOUR AU - Oh, Nicholas A. AU - Kampaktsis, Polydoros N. AU - Gallo, Michele AU - Guariento, Alvise AU - Weixler, Viktoria AU - Staffa, Steven J. AU - Avgerinos, Dimitrios V. AU - Colli, Andrea AU - Doulamis, Ilias P. PY - 2020 TI - An updated meta-analysis of MitraClip versus surgery for mitral regurgitation JF - Annals of Cardiothoracic Surgery; Vol 10, No 1 (January 29, 2021): Transcatheter Mitral Valve Replacement Y2 - 2020 KW - N2 - Background: Although studies demonstrate its feasibility, there is ongoing debate on the short and long-term outcomes of MitraClip versus surgical repair or mitral valve replacement (MVR). The objective of this meta-analysis is to compare the safety, morbidity, mortality and long-term function following MitraClip compared to MVR. Methods: Articles were searched in Pubmed and Cochrane databases for studies comparing outcomes of MitraClip and surgery on December 1, 2019. Eligible prospective, retrospective, randomized and non-randomized studies were reviewed. Results: A total of nine studies (n=1,873, MitraClip =533, MVR =644) were eligible for review. At baseline, MitraClip patients had more comorbidities than MVR patients, including myocardial infarction (P UR - https://www.annalscts.com/article/view/16770