%0 Journal Article %T Edge-to-edge repair: past challenge, current case selection and future advances %A Sorajja, Paul %A Ukaigwe, Anene C. %J Annals of Cardiothoracic Surgery %D 2020 %B 2020 %9 %! Edge-to-edge repair: past challenge, current case selection and future advances %K %X Severe mitral regurgitation (MR) is associated with heart failure and impaired survival with an annual mortality risk in excess of 5% per year for unoperated patients. Despite availability of surgical mitral valve interventions, as much as half of all patients with severe MR do not receive interventions. Transcatheter edge-to-edge repair with MitraClip has been a revolutionary therapy for MR, with over 100,000 treated patients worldwide. The usage has also expanded to different challenging anatomies as well as tricuspid regurgitation. Additionally, other transcatheter edge-to-edge repair devices are being studied. The evolution of these devices as well as what to expect in the future will be discussed here. %U https://www.annalscts.com/article/view/16781 %V 10 %N 1 %P 43-49 %@ 2304-1021