%0 Journal Article
%T Sex differences in outcomes following less-invasive left ventricular assist device implantation
%A Mariani, Silvia
%A Li, Tong
%A Bounader, Karl
%A Boethig, Dietmar
%A Schöde, Alexandra
%A Hanke, Jasmin S.
%A Michaelis, Jana
%A Napp, L. Christian
%A Berliner, Dominik
%A Dogan, Guenes
%A Lorusso, Roberto
%A Haverich, Axel
%A Schmitto, Jan D.
%J Annals of Cardiothoracic Surgery
%D 2021
%B 2021
%9 
%! Sex differences in outcomes following less-invasive left ventricular assist device implantation
%K 
%X Background: Worse outcomes in women compared to men undergoing left ventricular assist device (LVAD) implantation remain an underestimated problem in heart failure (HF) patients. With device miniaturization, less-invasive LVAD implantation techniques have gained relevance, but their impact on outcomes in women is unknown. This study investigates sex-related differences in patients undergoing LVAD implantation through less-invasive procedures.  Methods: This retrospective single-center cohort study included patients who underwent isolated LVAD implantation between 2011 and 2018 through less-invasive techniques. Propensity score matching (PSM) was utilized to balance preoperative heterogeneity. Primary endpoint was two-year survival, and secondary endpoints included long-term survival, surgical outcomes and postoperative adverse events.  Results: Baseline analysis of 191 patients (females 18.3%) showed differences in terms of age [female (median, 52; IQR, 47–61); male (median, 58.5; IQR, 49–66); P=0.005], underlying diagnosis (P
%U https://www.annalscts.com/article/view/16807
%V 10
%N 2
%P 255-267
%@ 2304-1021