%0 Journal Article %T Development of tricuspid regurgitation and right ventricular performance after implantation of centrifugal left ventricular assist devices %A Mulzer, Johanna %A Krastev, Hristo %A Hoermandinger, Christoph %A Meyer, Alexander %A Haese, Thomas %A Stein, Julia %A Müller, Marcus %A Schoenrath, Felix %A Knosalla, Christoph %A Starck, Christoph %A Falk, Volkmar %A Potapov, Evgenij %A Knierim, Jan %J Annals of Cardiothoracic Surgery %D 2021 %B 2021 %9 %! Development of tricuspid regurgitation and right ventricular performance after implantation of centrifugal left ventricular assist devices %K %X Background: Tricuspid regurgitation (TR) after left ventricular assist device (LVAD) implantation is associated with a poor prognosis. This study evaluates the development of TR and right ventricular (RV) performance after LVAD implantation. Methods: Retrospective analysis of patients who underwent LVAD implantation between March 2018 and June 2019. Patients who underwent concomitant tricuspid valve surgery and patients with congenital heart disease were excluded. Results: A total of 155 patients underwent LVAD implantation. Fourteen patients were excluded. Of the remaining patients, thirty-one died during the first six months, six were lost to follow-up and two underwent transplantation. 102 patients presented at 6.3 months (5.8 to 7.0). Patients were supported with HeartWare HVAD (74%) or HeartMate 3 (26%). 50.4% were rated as INTERMACS profile 1 or 2. At six months, systolic pulmonary artery pressure dropped from 36 to 21 mmHg (P Conclusions: TR can show an impressive improvement with LVAD support. Longitudinal RV function decreases; this appears to be compensated by transverse shortening. Late TR can develop independently from pre-operative parameters including TR. %U https://www.annalscts.com/article/view/16814 %V 10 %N 3 %P 364-374 %@ 2304-1021