TY - JOUR AU - Mulzer, Johanna AU - Krastev, Hristo AU - Hoermandinger, Christoph AU - Meyer, Alexander AU - Haese, Thomas AU - Stein, Julia AU - Müller, Marcus AU - Schoenrath, Felix AU - Knosalla, Christoph AU - Starck, Christoph AU - Falk, Volkmar AU - Potapov, Evgenij AU - Knierim, Jan PY - 2021 TI - Development of tricuspid regurgitation and right ventricular performance after implantation of centrifugal left ventricular assist devices JF - Annals of Cardiothoracic Surgery; Vol 10, No 3 (May 31, 2021): Continuous-Flow MCS in End-Stage Heart Failure II Y2 - 2021 KW - N2 - Background: Tricuspid regurgitation (TR) after left ventricular assist device (LVAD) implantation is associated with a poor prognosis. This study evaluates the development of TR and right ventricular (RV) performance after LVAD implantation. Methods: Retrospective analysis of patients who underwent LVAD implantation between March 2018 and June 2019. Patients who underwent concomitant tricuspid valve surgery and patients with congenital heart disease were excluded. Results: A total of 155 patients underwent LVAD implantation. Fourteen patients were excluded. Of the remaining patients, thirty-one died during the first six months, six were lost to follow-up and two underwent transplantation. 102 patients presented at 6.3 months (5.8 to 7.0). Patients were supported with HeartWare HVAD (74%) or HeartMate 3 (26%). 50.4% were rated as INTERMACS profile 1 or 2. At six months, systolic pulmonary artery pressure dropped from 36 to 21 mmHg (P Conclusions: TR can show an impressive improvement with LVAD support. Longitudinal RV function decreases; this appears to be compensated by transverse shortening. Late TR can develop independently from pre-operative parameters including TR. UR - https://www.annalscts.com/article/view/16814