%0 Journal Article %T Surgical ventricular reconstruction for ischemic cardiomyopathy—a systematic review and meta-analysis of 7,685 patients %A Ferrell, Brandon E. %A Jimenez, Diana C. %A Ahmad, Danial %A Malkani, Kabir %A Rosen, Jake L. %A Gaw, Gabriel %A Plestis, Konstadinos A. %A Guy, T. Sloane %A Massey, H. Todd %A Tchantchaleishvili, Vakhtang %J Annals of Cardiothoracic Surgery %D 2022 %B 2022 %9 %! Surgical ventricular reconstruction for ischemic cardiomyopathy—a systematic review and meta-analysis of 7,685 patients %K %X Background: Surgical ventricular reconstruction (SVR) has been used to control adverse ventricular remodeling and improve cardiac function in ischemic cardiomyopathy. The purpose of this systematic review and meta-analysis was to collect and analyze all available evidence on the utilization and efficacy of SVR. Methods: An electronic database search was performed to identify all retrospective and prospective studies on SVR for ischemic cardiomyopathy in the English literature from 2000 through 2020. A total of 92 articles with a collective 7,685 patients undergoing SVR were included in the final analysis. Results: The mean patient age was 61 years (95% CI: 59–63) and 80% (78–82%) were male. Congestive heart failure was present in 66% (54–78%) and angina in 58% (45–70%). Concomitant coronary artery bypass grafting was undertaken in 92% (90–93%) while 21% (18–24%) underwent mitral valve repair. Pre vs . post-SVR, significant improvement was seen in left ventricular ejection fraction (LVEF) [29.9% (28.8–31.2%) vs . 40.9% (39.4–42.4%), P vs . 45 mm (42.8–47.3), P vs . 58.23 mm (56.6–60), P 2 (79.3–88.4) vs . 46.8 mL/m2 (43.5–50.1), P 2 (73.6–85.7), P Conclusions: In patients with ischemic cardiomyopathy, SVR reduces left ventricular volumes and improves systolic function leading to symptomatic improvement. %U https://www.annalscts.com/article/view/16923 %V 11 %N 3 %P 226-238 %@ 2304-1021