TY - JOUR AU - Carroll, Adam M. AU - King, R. Wilson AU - Ghincea, Christian V. AU - Aftab, Muhammad AU - Reece, T. Brett PY - 2023 TI - Spinal cord protection for thoracoabdominal aortic aneurysm repair: from bench to bedside JF - Annals of Cardiothoracic Surgery; Vol 12, No 5 (September 28, 2023): Spinal Cord Protection Y2 - 2023 KW - N2 - This keynote lecture and corresponding presentation discuss the anatomy and pathophysiology surrounding spinal cord injury in aortic surgery. This article will discuss risk factors and mechanisms for spinal cord injury, including loss of direct and collateral spinal cord perfusion and ischemia-reperfusion injury. This review will examine these elements in both the laboratory and clinical setting, in addition to other neuroprotective strategies applied in clinical practice. Addressing spinal cord injury requires an integrated and considerate approach to simultaneously optimize spinal cord blood flow, promote collateralization and improve ischemic tolerance. Given the catastrophic clinical consequences for both the patient and their caregivers, continuing to investigate and examine spinal cord injury is of the utmost importance. UR - https://www.annalscts.com/article/view/17020