TY - JOUR AU - Nasir, Afsheen AU - Zafar, Mohammad A. AU - Abdelbaky, Mohamed AU - Papanikolaou, Dimitra AU - Ellauzi, Hesham AU - Shaikh, Maryam AU - Ziganshin, Bulat A. AU - Elefteriades, John A. PY - 2023 TI - Safety of cerebrospinal fluid drainage in descending and thoracoabdominal aortic replacement surgery JF - Annals of Cardiothoracic Surgery; Vol 12, No 5 (September 28, 2023): Spinal Cord Protection Y2 - 2023 KW - N2 - Background: Spinal cord injury (SCI) remains a significant morbidity of surgical repair of descending thoracic aortic aneurysms (DTAA) and thoracoabdominal aortic aneurysms (TAAA). We present our 17-year experience with cerebrospinal fluid drainage (CSFD) as a protective strategy during open surgical repair of descending and thoracoabdominal aortic disease. Methods: We conducted a retrospective chart review of 132 patients who underwent open surgical repair of DTAA and TAAA and dissections with concurrent use of CSFD for spinal cord protection. Information regarding survival, postoperative course, and complications related to CSFD use were extracted from electronic health records (EHR) and analyzed. Results: Mean patient age was 65.4±13.0 years, and 82 (62.1%) were male. A CSFD was successfully inserted in all patients. The mean hospital length of stay after surgery was 12.2±11.2 days, and in-hospital mortality was 7.6%. Postoperative transient paresis was observed in 5 patients (3.8%), and permanent paraplegia was seen in 4 (3.0%). CSFD related complications were reported in 25 patients (19%). Complications included persistent cerebrospinal fluid (CSF) leakage, blood-tinged CSF (with subdural hematoma reported in 3 patients) and spinal cutaneous fistula in 9 (7%), 14 (11%), and 1 (1%), respectively. Long term survival was 50.9% at 15 years. Conclusions: CSFD is associated with minor complications, without major sequalae. It is a safe practice and likely contributes innocuously to decreased SCI in patients undergoing open repair of DTAA and TAAA. UR - https://www.annalscts.com/article/view/17066