Systematic Reviews with or without Meta-analysis is a featured section with published systematic reviews and/or meta-analyses from the ACS addressing contemporary topics within the field of cardiothoracic surgery, based on the principles of evidence-based medicine. These reviews aim to identify, appraise, select and synthesize the highest-level evidence available in the current literature.

You are welcome to provide commentary and discuss any of the published systematic reviews. The Your Comments section will be available for general public viewing. If you wish to comment on a review article in this section, please locate the review article, click on the Your Comments tab and email your letter directly to the Editor-in-Chief. The authors of the original publication will be given the opportunity to respond to your comments. Please note that letters submitted to the Your Comments section are limited to 500 words. Join in the discussion today! All accepted letters will be published online within 48 hours and selected letters will be published in the print journal.