Welcome to Systematic Review

Systematic Reviews with or without Meta-analysis is a featured section with published systematic reviews and/or meta-analyses from the ACS addressing contemporary topics within the field of cardiothoracic surgery, based on the principles of evidence-based medicine. These reviews aim to identify, appraise, select and synthesize the highest-level evidence available in the current literature.

You are welcome to provide commentary and discuss any of the published systematic reviews. The Your Comments section will be available for general public viewing. If you wish to comment on a review article in this section, please locate the review article, click on the Your Comments tab and email your letter directly to the Editor-in-Chief. The authors of the original publication will be given the opportunity to respond to your comments. Please note that letters submitted to the Your Comments section are limited to 500 words. Join in the discussion today! All accepted letters will be published online within 48 hours and selected letters will be published in the print journal.

Vol 14, No 5 (September 30, 2025): Evolution of Elephant Trunk II

Mid-to-long-term outcomes of the frozen elephant trunk procedure in aortic pathology: a systematic review and meta-analysis

Aditya Eranki, David Downes, Benjamin Muston, Connor Debs, Daksh Tyagi, Liam Munir, Ashley R. Wilson-Smith, Aashray Gupta
Full Text (1178) | PDF | Open Access

Vol 14, No 1 (January 26, 2025): Heart Transplantation In Controlled Donation After Circulatory Death II

Donation after circulatory death transplantation: a systematic review and meta-analysis of outcomes and methods of donation

Jarrod Jolliffe, John Brookes, Michael Williams, Elizabeth Walker, Paul Jansz, Alasdair Watson, Peter MacDonald, Julian Smith, Jayme Bennetts, Massimo Boffini, Antonio Loforte
Full Text (8652) | PDF | Open Access

Cardiac transplantation in controlled donation after circulatory death: a meta-analysis of long-term survival using reconstructed time-to-event data

Benjamin T. Muston, Winky Lo, Aditya Eranki, Massimo Boffini, Antonio Loforte
Full Text (4913) | PDF | Open Access

Vol 14, No 2 (March 31, 2025): TAVR Explant

Transcatheter versus surgical aortic valve replacement in low- to intermediate-risk patients: a meta-analysis of reconstructed time-to-event data

Tomonari Shimoda, Yoshihisa Miyamoto, Junichi Shimamura, Hiroki Ueyama, Yujiro Yokoyama, Michel Pompeu Sá, Tsuyoshi Kaneko, Tomo Ando, Hisato Takagi, Shinichi Fukuhara, Toshiki Kuno
Full Text (11006) | PDF | Open Access

The current state of transcatheter aortic valve replacement explant: an updated systematic review

Michel Pompeu Sá, Eishan Ashwat, Xander Jacquemyn, Danial Ahmad, James A. Brown, Derek Serna-Gallegos, Asishana Osho, Jordan P. Bloom, Ibrahim Sultan
Full Text (3824) | PDF | Open Access

Vol 13, No 6 (November 30, 2024): Heart Transplantation In Controlled Donation After Circulatory Death I

Heart transplantation from donation after circulatory death: a meta-analysis of national registries

Vincenzo Tarzia, Matteo Ponzoni, Danila Azzolina, Luca Vedovelli, Nicola Pradegan, Dario Gregori, Gino Gerosa
Full Text (4771) | PDF | Open Access

Vol 13, No 5 (September 29, 2024): Robotic Coronary Artery Bypass Grafting II

The outcomes of robotic-assisted coronary artery bypass grafting surgery in the Atlantic demographic—a systematic review and meta-analysis of the literature

Ashley R. Wilson-Smith, Christian J. Wilson-Smith, Jemilla Strode Smith, Rowen Osborn, Winky Lo, Dominic Ng, Bridget Hwang, Justin Shaw, Benjamin T. Muston, Michael L. Williams, Aditya Eranki, Aashray Gupta, Lucy Manuel, Malgorzata Szpytma, Luca Borruso, Advait Pandya, David Downes
Full Text (8954) | PDF | Open Access

Vol 13, No 4 (July 31, 2024): Robotic Coronary Artery Bypass Grafting I

Systematic review and meta-analysis of two decades of reported outcomes for robotic coronary artery bypass grafting

Bridget Hwang, Justin Ren, Katherine Wang, Michael L. Williams, Tristan D. Yan
Full Text (13726) | PDF | Open Access

Vol 13, No 3 (May 31, 2024): Aortic Annular Enlargement

Early and mid-term outcomes of aortic annular enlargement: a systematic review and meta-analysis

Dustin Tanaka, Dominique Vervoort, Amine Mazine, Lina Elfaki, Jennifer C. Y. Chung, Jan O. Friedrich, Maral Ouzounian
Full Text (3987) | PDF | Open Access

Vol 13, No 2 (March 29, 2024): Atrial Fibrillation Management II

Atrial fibrillation ablation during robotic mitral valve surgery: a systematic review and meta-analysis

Aditya Eranki, Benjamin Muston, Dominic Ng, Ashley R. Wilson-Smith, Aashray K. Gupta
Full Text (3377) | PDF | Open Access

The outcomes of concomitant catheter ablation in non-mitral valve cardiac surgery—a systematic review and meta-analysis of the literature

Ashley R. Wilson-Smith, Christian J. Wilson-Smith, Jemilla Strode Smith, Dominic Ng, Benjamin T. Muston, Aditya Eranki, Michael L. Williams, Nathan Ussher, Aashray K. Gupta
Full Text (3706) | PDF | Open Access

Vol 13, No 1 (January 30, 2024): Atrial Fibrillation Management I

Surgical ablation of atrial fibrillation during mitral valve surgery: a systematic review and meta-analysis

Aditya Eranki, Benjamin Muston, Ashley Wilson-Smith, Christian Wilson-Smith, Michael Williams, Matthew Doyle, Martin Misfeld
Full Text (9086) | PDF | Open Access

Mid-to-long-term recurrence of atrial fibrillation in surgical treatment vs. catheter ablation: a meta-analysis using aggregated survival data

Benjamin T. Muston, James Bilbrough, Aditya Eranki, Christian Wilson-Smith, Ashley R. Wilson-Smith
Full Text (11088) | PDF | Open Access

Vol 12, No 6 (November 27, 2023): Aortic Disease in Women

Sex differences in long-term outcomes following surgery for acute type A aortic dissection: a systematic review and meta-analysis

Nitish Bhatt, Rodolfo V. Rocha, Farid Foroutan, Michael W. A. Chu, Maral Ouzounian, Daniyal N. Mahmood, Jennifer Chia-Ying Chung
Full Text (3605) | PDF | Open Access

Vol 12, No 5 (September 28, 2023): Spinal Cord Protection

Open, closed or a bit of both: a systematic review and meta-analysis of staged thoraco-abdominal aortic aneurysm repair

Benjamin T. Muston, James Bilbrough, Ymer Bushati, Ashley R. Wilson-Smith, Martin Misfeld, Tristan Yan
Full Text (6039) | PDF | Open Access

Spinal cord injury after open and endovascular repair of descending thoracic aneurysm and thoracoabdominal aortic aneurysm: an updated systematic review and meta-analysis

Talal Alzghari, Kevin R. An, Lamia Harik, Mohamed Rahouma, Arnaldo Dimagli, Roberto Perezgorvas-Olaria, Michelle Demetres, Gianmarco Cancelli, Giovanni Soletti Jr, Christopher Lau, Leonard N. Girardi, Mario Gaudino
Full Text (6144) | PDF | Open Access

Prophylactic cerebrospinal fluid drainage and spinal cord ischemia in thoracic and thoracoabdominal endovascular procedures: a systematic review and meta-analysis

Cheng-Hao Jacky Chen, Henry Jiang, Vinh Dat David Nguyen
Full Text (8047) | PDF | Open Access

Vol 12, No 4 (July 31, 2023): Three Decades of Aortic Valve-Sparing Operations II

The outcomes of three decades of the David and Yacoub procedures in bicuspid aortic valve patients—a systematic review and meta-analysis

Ashley R. Wilson-Smith, Christian J. Wilson-Smith, Jemilla Strode Smith, Dominic Ng, Benjamin T. Muston, Aditya Eranki, Michael L. Williams
Full Text (7440) | PDF | Open Access

Vol 12, No 3 (May 31, 2023): Three Decades of Aortic Valve-Sparing Operations I

Valve-sparing aortic root replacement using the reimplantation (David) technique: a systematic review and meta-analysis on survival and clinical outcome

Stefano Mastrobuoni, Pascal J. Govers, Kevin M. Veen, Jama Jahanyar, Silke van Saane, Antonio Segreto, Luca Zanella, Laurent de Kerchove, Johanna J. M. Takkenberg, Bardia Arabkhani
Full Text (7169) | PDF | Open Access

Vol 12, No 2 (March 31, 2023): Uniportal Robotic-Assisted Thoracic Surgery II

The perioperative outcomes of uniportal robotic-assisted thoracic surgeries—a systematic review and meta-analysis of surgical cohort studies and case reports

Ashley R. Wilson-Smith, Christian J. Wilson-Smith, Naomi Anning, Benjamin Muston, Aditya Eranki, Michael L. Williams, Diego Gonzalez-Rivas, Tristan D. Yan, James Ephraums
Full Text (4274) | PDF | Open Access

Vol 12, No 1 (January 31, 2023): Uniportal Robotic-Assisted Thoracic Surgery I

The learning curve of the robotic-assisted lobectomy—a systematic review and meta-analysis

Ashley R. Wilson-Smith, Naomi Anning, Benjamin Muston, Aditya Eranki, Michael L. Williams, Christian J. Wilson-Smith, Diego G. Rivas, Tristan D. Yan
Full Text (4542) | PDF | Open Access

Vol 11, No 6 (November 29, 2022): Robotic Mitral Valve Surgery II

Systematic review and meta-analysis of mid-term survival, reoperation, and recurrent mitral regurgitation for robotic-assisted mitral valve repair

Michael L. Williams, Aditya Eranki, Andrew Mamo, Ashley Wilson-Smith, Bridget Hwang, Ramanen Sugunesegran, Tristan Yan, Emiliano Navarra, T. Sloane Guy, Johannes Bonatti
Full Text (4896) | PDF | Open Access

Vol 11, No 5 (September 30, 2022): Robotic Mitral Valve Surgery I

Robotic versus conventional sternotomy mitral valve surgery: a systematic review and meta-analysis

Michael L. Williams, Bridget Hwang, Linna Huang, Ashley Wilson-Smith, John Brookes, Aditya Eranki, Tristan D. Yan, T. Sloane Guy, Johannes Bonatti
Full Text (10033) | PDF | Open Access

Vol 11, No 4 (July 29, 2022): Bicuspid Aortic Valve

Incidence of bicuspid valve related aortic dissection: a systematic review and meta-analysis

Ashley R. Wilson-Smith, Aditya Eranki, Benjamin Muston, Harish Kamalanathan, Amanda Yung, Michael L. Williams, Prachi Sahai, Caroline Zi, Hector Michelena
Full Text (5156) | PDF | Open Access

Procedural and clinical outcomes of transcatheter aortic valve replacement in bicuspid aortic valve patients: a systematic review and meta-analysis

Cheng-Hao Jacky Chen, Henry Jiang, Owen Martin, Ashley R. Wilson-Smith
Full Text (6480) | PDF | Open Access

Vol 11, No 3 (May 31, 2022): Surgical & Non-Surgical Management of Mechanical Complications of AMI

Systematic review and meta-analysis of the mechanical complications of ischemic heart disease: papillary muscle rupture, left ventricle rupture and post-infarct ventricular septal defect

Campbell D. Flynn, Paraskevi Morris, Lucy Manuel, Matteo Matteucci, Daniele Ronco, Giulio Massimi, Federica Torchio, Roberto Lorusso
Full Text (8707) | PDF | Open Access

Surgical management for mechanical complications of acute myocardial infarction: a systematic review of long-term outcomes

Sarah Yousef, Ibrahim Sultan, Helena M. VonVille, Kevin Kahru, George J. Arnaoutakis
Full Text (6976) | PDF | Open Access

Surgical treatment of post-infarction papillary muscle rupture: systematic review and meta-analysis

Giulio Massimi, Matteo Matteucci, Mariusz Kowalewski, Daniele Ronco, Federica Jiritano, Cesare Beghi, Paolo Severgnini, Roberto Lorusso
Full Text (8937) | PDF | Open Access

Surgical ventricular reconstruction for ischemic cardiomyopathy—a systematic review and meta-analysis of 7,685 patients

Brandon E. Ferrell, Diana C. Jimenez, Danial Ahmad, Kabir Malkani, Jake L. Rosen, Gabriel Gaw, Konstadinos A. Plestis, T. Sloane Guy, H. Todd Massey, Vakhtang Tchantchaleishvili
Full Text (4793) | PDF | Open Access

Effects of concomitant coronary artery bypass grafting on early and late mortality in the treatment of post-infarction mechanical complications: a systematic review and meta-analysis

Daniele Ronco, Claudio Corazzari, Matteo Matteucci, Giulio Massimi, Michele Di Mauro, Justine M. Ravaux, Cesare Beghi, Roberto Lorusso
Full Text (5106) | PDF | Open Access

Vol 11, No 2 (March 31, 2022): PTE in Chronic Thromboembolic Pulmonary Hypertension and Disease

Pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension: a systematic review

John D. L. Brookes, Crystal Li, Sally T. W. Chung, Elizabeth M. Brookes, Michael L. Williams, Nicholas McNamara, Sofia Martin-Suarez, Antonio Loforte
Full Text (6891) | PDF | Open Access

Vol 10, No 6 (November 28, 2021): Thoracic Aortic Endovascular Solutions I

Endovascular repair of acute complicated type B aortic dissection—systematic review and meta-analysis of long-term survival and reintervention

Ashley R. Wilson-Smith, Benjamin Muston, Harish Kamalanathan, Amanda Yung, Cheng-Hao Jacky Chen, Prachi Sahai, Aditya Eranki
Full Text (7536) | PDF | Open Access

Vol 11, No 1 (January 24, 2022): Thoracic Aortic Endovascular Solutions II

Thoracic endovascular repair of chronic type B aortic dissection: a systematic review

Michael L. Williams, Madeleine de Boer, Bridget Hwang, Bruce Wilson, John Brookes, Nicholas McNamara, David H. Tian, Timothy Shiraev, Ourania Preventza
Full Text (12328) | PDF | Open Access

Vol 10, No 5 (September 29, 2021): Transcatheter Valve-in-Valve

Transcatheter mitral valve replacement for degenerated mitral bioprostheses: a systematic review

Mackram F. Eleid, Charanjit S. Rihal, Mayra E. Guerrero
Full Text (6892) | PDF | Open Access

Vol 10, No 4 (July 30, 2021): Ross Procedure

Systematic review and meta-analysis of long-term outcomes in adults undergoing the Ross procedure

Campbell D. Flynn, Joshua H. De Bono, Benjamin Muston, Nivedita Rattan, David H. Tian, Marco Larobina, Michael O’Keefe, Peter Skillington
Full Text (8603) | PDF | Open Access

The Ross procedure in children: a systematic review

Morgan K. Moroi, Emile A. Bacha, David M. Kalfa
Full Text (10592) | PDF | Open Access

Vol 10, No 3 (May 31, 2021): Continuous-Flow MCS in End-Stage Heart Failure II

Contemporary outcomes of continuous-flow biventricular assist devices

James Farag, Kei Woldendorp, Nicholas McNamara, Paul G. Bannon, Silvana F. Marasco, Antonio Loforte, Evgenij V. Potapov
Full Text (9825) | PDF | Open Access

Development of malignancies and their outcomes in patients supported on continuous-flow left ventricular assist devices—a systematic review

Elizabeth J. Maynes, Jonathan S. Gordon, Matthew P. Weber, Thomas J. O’Malley, Tyler M. Bauer, Chelsey T. Wood, Rohinton J. Morris, Louis E. Samuels, John W. Entwistle, H. Todd Massey, Vakhtang Tchantchaleishvili
Full Text (7576) | PDF | Open Access
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